Reconstitute using the supplied solvent with the provided transfer system. Gently swirl until fully dissolved. Do not shake vigorously. Inspect for particulate matter and clarity. For a step by step guide, follow the reconstitution guide. 

Additional required items may include a luer lock syringe for administration and alcohol wipes for aseptic vial preparation. For pooling, an IV mini-bag can be used for transfer.  

Please consult your transfusion medicine team regarding your institutions best practices and what is provided with your blood products.  

Follow the monograph and local policy. Provide a bedside example for a 70 kg adult so nursing can proceed without calculation delays.

The reconstitution device supplied with Fibryga has a dual integrated filter, thus, administration of Fibryga does not require a separate filtration process. Check local instructions for the supplied kit.

No specific manufacturer studies exist for rapid infusers. If local policy allows, use clinical judgement, a dedicated line, and close observation. 

Do not mix with other medicinal products in the same line. Use a separate lumen. If unavoidable, stop other infusions, flush with a compatible fluid, administer Fibryga, then flush.

Normal saline is preferred where specified. Confirm any alternatives in local policy. Avoid concurrent calcium administration through the same lumen.

Yes if separate lumens are used and there is no mixing in the line. 

Record every lot. When pooling, maintain traceability for each vial used.

Administer as soon as possible. If a delay is unavoidable, stability of the reconstituted solution has been demonstrated for up to 24 hours at +25°C, provided sterility of the stored product is maintained. Follow the monograph and site policy limits. Routine ward storage is discouraged.

Check the monograph for exact sodium per vial. This is usually considerably less than cryoprecipitate or plasma volumes.