Translate your typical cryo order into grams, then give an equivalent amount as concentrate, or start with 50 to 70 mg per kg when baseline is unknown. Re-check and adjust to target rather than repeating the old cryo habit.

Immediate availability without thawing, standardized content per vial, small volume, and reduced transfusion reactions allow faster, predictable correction during time-critical care.

Fibryga is made from pooled plasma with multiple dedicated pathogen reduction steps and validated viral inactivation or removal across the manufacturing process, and each lot is tested before release. Cryoprecipitate is derived from plasma components with standard donor screening and testing but does not undergo the same dedicated viral inactivation steps used in solvent-detergent plasma or certain concentrates. Residual risk with modern screening is already very low for both, and concentrates add further reduction through process design. Follow local blood service guidance.