Question 1

Which test should I rely on for dosing

admin_fibryga_2025 · Accepted Answer

Clauss fibrinogen is the reference. Where available, ROTEM or TEG may guide both the trigger and the effect of therapy with faster turnaround.

Question 2

How often should I repeat labs?

admin_fibryga_2025 · Accepted Answer

For ongoing major bleeding, re-check after the first dose, then at intervals dictated by hemorrhage severity, often every 4 to 6 hours in the first day or at the next viscoelastic cycle.

Question 3

What if fibrinogen fails to rise as expected?

admin_fibryga_2025 · Accepted Answer

Consider ongoing consumption, dilution, hyperfibrinolysis, laboratory timing relative to infusion, or sampling issues. Reassess dosing and consult hematology.

Question 4

Which test should I rely on for dosing

admin_fibryga_2025 · Accepted Answer

Clauss fibrinogen is the reference. Where available, ROTEM or TEG may guide both the trigger and the effect of therapy with faster turnaround.

Question 5

How often should I repeat labs?

admin_fibryga_2025 · Accepted Answer

For ongoing major bleeding, re-check after the first dose, then at intervals dictated by hemorrhage severity, often every 4 to 6 hours in the first day or at the next viscoelastic cycle.

Question 6

What if fibrinogen fails to rise as expected?

admin_fibryga_2025 · Accepted Answer

Consider ongoing consumption, dilution, hyperfibrinolysis, laboratory timing relative to infusion, or sampling issues. Reassess dosing and consult hematology.

Question 7

Which test should I rely on for dosing

admin_fibryga_2025 · Accepted Answer

Clauss fibrinogen is the reference. Where available, ROTEM or TEG may guide both the trigger and the effect of therapy with faster turnaround.

Question 8

How often should I repeat labs?

admin_fibryga_2025 · Accepted Answer

For ongoing major bleeding, re-check after the first dose, then at intervals dictated by hemorrhage severity, often every 4 to 6 hours in the first day or at the next viscoelastic cycle.

Question 9

What if fibrinogen fails to rise as expected?

admin_fibryga_2025 · Accepted Answer

Consider ongoing consumption, dilution, hyperfibrinolysis, laboratory timing relative to infusion, or sampling issues. Reassess dosing and consult hematology.

Question 10

Which test should I rely on for dosing

admin_fibryga_2025 · Accepted Answer

Clauss fibrinogen is the reference. Where available, ROTEM or TEG may guide both the trigger and the effect of therapy with faster turnaround.

Question 11

How often should I repeat labs?

admin_fibryga_2025 · Accepted Answer

For ongoing major bleeding, re-check after the first dose, then at intervals dictated by hemorrhage severity, often every 4 to 6 hours in the first day or at the next viscoelastic cycle.

Question 12

What if fibrinogen fails to rise as expected?

admin_fibryga_2025 · Accepted Answer

Consider ongoing consumption, dilution, hyperfibrinolysis, laboratory timing relative to infusion, or sampling issues. Reassess dosing and consult hematology.

Question 13

Which test should I rely on for dosing

admin_fibryga_2025 · Accepted Answer

Clauss fibrinogen is the reference. Where available, ROTEM or TEG may guide both the trigger and the effect of therapy with faster turnaround.

Question 14

How often should I repeat labs?

admin_fibryga_2025 · Accepted Answer

For ongoing major bleeding, re-check after the first dose, then at intervals dictated by hemorrhage severity, often every 4 to 6 hours in the first day or at the next viscoelastic cycle.

Question 15

What if fibrinogen fails to rise as expected?

admin_fibryga_2025 · Accepted Answer

Consider ongoing consumption, dilution, hyperfibrinolysis, laboratory timing relative to infusion, or sampling issues. Reassess dosing and consult hematology.

Question 16

Which test should I rely on for dosing

admin_fibryga_2025 · Accepted Answer

Clauss fibrinogen is the reference. Where available, ROTEM or TEG may guide both the trigger and the effect of therapy with faster turnaround.

Question 17

How often should I repeat labs?

admin_fibryga_2025 · Accepted Answer

For ongoing major bleeding, re-check after the first dose, then at intervals dictated by hemorrhage severity, often every 4 to 6 hours in the first day or at the next viscoelastic cycle.

Question 18

What if fibrinogen fails to rise as expected?

admin_fibryga_2025 · Accepted Answer

Consider ongoing consumption, dilution, hyperfibrinolysis, laboratory timing relative to infusion, or sampling issues. Reassess dosing and consult hematology.

Question 19

Which test should I rely on for dosing

admin_fibryga_2025 · Accepted Answer

Clauss fibrinogen is the reference. Where available, ROTEM or TEG may guide both the trigger and the effect of therapy with faster turnaround.

Question 20

How often should I repeat labs?

admin_fibryga_2025 · Accepted Answer

For ongoing major bleeding, re-check after the first dose, then at intervals dictated by hemorrhage severity, often every 4 to 6 hours in the first day or at the next viscoelastic cycle.

Question 21

What if fibrinogen fails to rise as expected?

admin_fibryga_2025 · Accepted Answer

Consider ongoing consumption, dilution, hyperfibrinolysis, laboratory timing relative to infusion, or sampling issues. Reassess dosing and consult hematology.

Question 22

Which test should I rely on for dosing

admin_fibryga_2025 · Accepted Answer

Clauss fibrinogen is the reference. Where available, ROTEM or TEG may guide both the trigger and the effect of therapy with faster turnaround.

Question 23

How often should I repeat labs?

admin_fibryga_2025 · Accepted Answer

For ongoing major bleeding, re-check after the first dose, then at intervals dictated by hemorrhage severity, often every 4 to 6 hours in the first day or at the next viscoelastic cycle.

Question 24

What if fibrinogen fails to rise as expected?

admin_fibryga_2025 · Accepted Answer

Consider ongoing consumption, dilution, hyperfibrinolysis, laboratory timing relative to infusion, or sampling issues. Reassess dosing and consult hematology.

Question 25

Which test should I rely on for dosing

admin_fibryga_2025 · Accepted Answer

Clauss fibrinogen is the reference. Where available, ROTEM or TEG may guide both the trigger and the effect of therapy with faster turnaround.

Question 26

How often should I repeat labs?

admin_fibryga_2025 · Accepted Answer

For ongoing major bleeding, re-check after the first dose, then at intervals dictated by hemorrhage severity, often every 4 to 6 hours in the first day or at the next viscoelastic cycle.

Question 27

What if fibrinogen fails to rise as expected?

admin_fibryga_2025 · Accepted Answer

Consider ongoing consumption, dilution, hyperfibrinolysis, laboratory timing relative to infusion, or sampling issues. Reassess dosing and consult hematology.

Question 28

Which test should I rely on for dosing

admin_fibryga_2025 · Accepted Answer

Clauss fibrinogen is the reference. Where available, ROTEM or TEG may guide both the trigger and the effect of therapy with faster turnaround.

Question 29

How often should I repeat labs?

admin_fibryga_2025 · Accepted Answer

For ongoing major bleeding, re-check after the first dose, then at intervals dictated by hemorrhage severity, often every 4 to 6 hours in the first day or at the next viscoelastic cycle.

Question 30

What if fibrinogen fails to rise as expected?

admin_fibryga_2025 · Accepted Answer

Consider ongoing consumption, dilution, hyperfibrinolysis, laboratory timing relative to infusion, or sampling issues. Reassess dosing and consult hematology.

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Laboratory targets and monitoring

Which test should I rely on for dosing

How often should I repeat labs?

What if fibrinogen fails to rise as expected?